Adjunct duties for karyopherins: regulating septin sumoylation
Authors: Panse VG, Hurt E
CellNetworks People: Hurt Ed
Journal: Dev Cell. 2007 May;12(5):669-70

Karyopherins are shuttling transport receptors regulated by the small GTPase Ran, which move cargo between the nucleus and cytoplasm by passing through the nuclear pore complexes. A recent paper in Journal of Cell Biology (Makhnevych et al., 2007) highlights an additional role for karyopherins during mitosis, in regulating the sumoylation status of the septin rings.