Direct monitoring of formation and dissociation of individual metal complexes by single-molecule fluorescence spectroscopy
2007
Authors: Kiel A, Kovacs J, Mokhir A, Krämer R, Herten DP
CellNetworks People: Herten Dirk-Peter
Journal: Angew Chem Int Ed Engl. 2007 Apr 27;46(18):3363-3366. doi: 10.1002/anie.200604965

For the observation of the coordination states of individual copper(II) chelate complexes in thermodynamic equilibrium (see picture; TMR=tetramethylrhodamine), single-molecule fluorescence spectroscopy can be used. Application of time-resolved single-molecule spectroscopy opens new prospects for the investigation of reactions in the coordination sphere of metal complexes.