Competition for cytokines: T(reg) cells take all
|Authors:||Scheffold A, Murphy KM, Höfer T|
|CellNetworks People:||Höfer Thomas|
|Journal:||Nat Immunol. 2007 Dec;8(12):1285-7. doi: 10.1038/ni1207-1285|
Thymus-derived regulatory T cells are thought to suppress target cells by either a cell contact–dependent mechanism or the production of inhibitory cytokines. A new study suggests a third strategy of apoptosis induced by the consumption of interleukin 2 and other T cell growth factors by regulatory T cells.