Berd Bukau (left) and Ed Hurt were awarded with an ERC Avanced for outstanding research in Europe. Photo: Schwerdt
In the ERC-supported research project “TransFold – Molecular Biology of Nascent Chains: Co-translational Folding and Assembly of Proteins in Eukaryotes” Prof. Bukau and his team are focusing on the process of protein folding. The central question is how a cell can efficiently “fold” amino acid chains into functional proteins with a three-dimensional structure and assemble them to protein complexes. Prof. Bukau is director of the Centre for Molecular Biology of Heidelberg University (ZMBH) and at the same time does research at the German Cancer Research Centre (DKFZ). Approximately 2.1 million euros are available to fund the research work, which will start in summer 2017.
Prof. Hurt’s project on the biogenesis of ribosomes will be funded for a period of five years. The researchers in his team want to study the largely unexplored processes that take place in the initial phase of the manufacture of these cellular protein factories. The results of the research could contribute to a greater understanding of ribosomopathies – diseases caused by impaired ribosome biogenesis. In the funded project, entitled “Encapsulated Eukaryotic Ribosome Assembly”, Prof. Hurt and his team will study the earliest known ribosomal precursor, the 90S pre-ribosome. The research, which is scheduled to begin in 2018, will receive ERC funding of approximately two million euros. Ed Hurt teaches and conducts research at the Heidelberg University Biochemistry Center (BZH).
Please find more information in the official press releases issued by Heidelberg University
Prof. Dr Eduard Hurt
Heidelberg University Biochemistry Center (BZH)
Tel. +49 6221 54-4173
Prof. Dr Bernd Bukau
Centre for Molecular Biology of Heidelberg University (ZMBH)
Tel. +49 6221 54-6795
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Tel. +49 6221 54-2311